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KMID : 0352719890130010024
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Journal of Ginseng Research
1989 Volume.13 No. 1 p.24 ~ p.29
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김웅
정노팔
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Abstract
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The tumoricidal activity of marine macrophage against K562 tumor cells was studied in the presence of lipopolysaccharide(LPS) and ginseng saponin. 1 The tumoricidal activity was increased more by LPS treatment with ginseng saponin (44% in 24 hours) than by LPS only (22% in 24 hours). In the case of diol saponin, the tumoricidal activity was increased as much as 35% at concentrations of 10-3 to 1034%. Triol saponin increased the tumoricidal activity more than LPS only treatment at each concentration . 2. When total, dial and triol saponin were added to K.562 tumor cell in various concentration without macrophage, it was found that the ginseng saponin hall no tumoricidal effect. This result suggests that ginseng saponin increases the tumoricidal activity of K562 tumor celts through the tumoricidal activity of the macrophage.
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KEYWORD
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#Panax ginseng C #A #Meyer #ginseng saponin #lipopolysaccharide #macrophage #tumor cells #tumoricidal activity
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